Associate Director, Principal Data Engineer

Vir Biotechnology Inc. is a clinical-stage biopharmaceutical company focused on powering the immune system to transform lives by discovering and developing medicines for serious infectious diseases and cancer. Its clinical-stage portfolio includes programs for chronic hepatitis delta and multiple PRO-XTEN dual-masked T-cell engagers across validated targets in solid tumor indications. Vir Biotechnology also has a preclinical portfolio of programs across a range of infectious diseases and oncologic malignancies. Vir Biotechnology has exclusive rights to the universal PRO-XTEN masking platform for oncology and infectious disease. PRO-XTEN is a trademark of Amunix Pharmaceuticals Inc. a Sanofi company. We believe the success of our colleagues drives the success of our mission. We are committed to creating a company where everyone feels supported and encouraged to give their best. THE OPPORTUNITY Vir Biotechnology is seeking an Associate Director Principal Data Engineer to lead scalable data cloud software and AI-enabled research platforms that support scientific discovery clinical data analysis and program decision-making. This role will build the foundation for AI-powered research workflows including AI agents for research QC/QA and scientific/regulatory reporting while partnering across Research Clinical Data Science TechOps Competitive Intelligence and IT.

The ideal candidate

is a forward-thinking technical leader who combines expertise in data engineering scientific software AWS cloud platforms and practical AI implementation to transform complex scientific data into connected searchable and actionable insights. They excel at partnering with scientists data scientists and engineers to build trusted scalable solutions that accelerate research while maintaining the highest standards of data quality governance validation and reliability. Reporting to the Senior Director Research this role is based in San Francisco with an expectation of three days per week in the office

WHAT YOU'LL DO

Build AI-enabled research workflows and agents that help scientists search analyze summarize and connect Vir-generated Develop AI agents for TCE research insights Experimenta QC/QA review and scientific/regulatory report Design trusted LLM RAG knowledge-search and agentic AI workflows with traceability validation governance and human Lead development and integration of scientific platforms including SeqAssembler HPD/dAIsY SASTRY OPAL Miner and Build scalable research and clinical data pipelines for bioinformatics genomics machine learning and scientific decision-making. Architect and operate AWS cloud infrastructure for AI/ML bioinformatics clinical analysis and large-scale scientific data Strengthen data quality metadata lineage observability security governance and platform Partner cross-functionally to align data cloud application and AI solutions with program Provide senior technical leadership across architecture engineering practices mentoring and roadmap WHO YOU ARE AND WHAT YOU BRING BS/MS in Computer Science Data Engineering Bioinformatics Computational Biology Engineering or a related technical 12+ years of experience in data engineering software engineering scientific computing cloud architecture or scientific application Strong hands-on experience with Python and/or Java including scalable data pipelines APIs services and production-grade data Experience building AI/ML-enabled scientific applications using leading LLMs such as GPT Claude Gemini or similar models including RAG knowledge search agentic workflows and governance Experience integrating LIMS ELN scientific data platforms or experiment-management systems such as Experimenta to support data capture analysis quality review and scientific Strong AWS cloud infrastructure experience including compute storage networking security data processing monitoring automation and operational Experience with modern cloud-based data platforms and workflow technologies such as Databricks Snowflake Redshift Spark Airflow Nextflow or similar Experience supporting bioinformatics genomics machine learning clinical healthcare or other scientific data Strong knowledge of data modeling metadata management data quality observability governance lineage and platform Demonstrated technical leadership including architecture ownership roadmap development mentoring and cross-functional Excellent communication and collaboration skills across Research Clinical Data Science IT and business LI-AS1 LI-Onsite WHO WE ARE AND WHAT

WE OFFER

The expected salary range for this position is $176500 to $246500 per year. Actual pay will be determined based on experience qualifications geographic location and other job-related factors. Vir Biotechnology's compensation and benefits are aligned with the current market and commensurate with the person’s experience and qualifications. All full-time employees receive a package that includes compensation bonus and equity as well as many other Vir Biotechnology benefits and perks such as health and welfare benefit plans non-accrual paid time off company shut down for holidays commuter benefits 401K match and lunch each day in the office. Applicants must currently be authorized to work for any employer in the U.S. We are unable to sponsor or take over sponsorship of an employment Visa at this time. All employment decisions at Vir Biotechnology are based on legitimate non-discriminatory business requirements job duties and individual qualifications. Employment decisions are made without regard to any legally protected characteristics. This commitment extends to all management practices and decisions including recruitment and hiring compensation appraisal systems promotions training and career development programs. Vir Biotechnology also strongly commits to providing employees with a work environment free of unlawful conduct or harassment. Vir Biotechnology Human Resources leads recruitment and employment for Vir Biotechnology. Unsolicited resumes sent to the company from recruiters do not constitute any type of relationship between the recruiter and Vir Biotechnology and do not obligate us to pay fees should we hire from those resumes. We ask that external recruiters and/or agencies not contact or present candidates directly to our hiring manager or employees. For hires based in the United States Vir Biotechnology participates in E-Verify Candidate

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